Minuman Manis dan Hipertensi dalam Perspektif Epidemiologi: Sintesis Bukti Ilmiah

Authors

  • Febry Istyanto Poltekkes Kemenkes Jayapura
  • Liza Virgianti Universitas Diponegoro
  • Ika Wijayanti Poltekkes Kemenkes Semarang
  • Sophian Aswar Poltekkes Kemenkes Jayapura

DOI:

https://doi.org/10.63265/jkti.v4i3.285

Keywords:

blood pressure, epidemiological synthesis, energy drinks, hypertension, sugar-sweetened beverages

Abstract

Background: The rising global burden of hypertension presents a massive public health challenge, with its mitigation heavily tied to modifiable dietary factors. Among these, the escalating intake of sugar-sweetened beverages (SSBs) has emerged as a significant dietary risk. Objectives: This study aims to synthesize recent epidemiological evidence regarding the association between various types of sweetened beverages and the risk of hypertension. Methods: A narrative-analytical review was conducted by retrieving observational studies and meta-analyses published between 2023 and 2026 from the Scopus database using explicit keyword combinations targeting SSBs, prospective cohorts, and blood pressure outcomes. Findings: Synthesized data reveals that high consumption of traditional SSBs significantly increases hypertension risk by 13% (RR: 1.13) and elevates systolic blood pressure in children, primarily driven by excess liquid calories. Artificially sweetened beverages (ASBs) show a 14% risk increase in observational data, potentially confounded by reverse causation, whereas acute pure fructose ingestion triggers rapid transient blood pressure elevation. Energy drinks induce rapid 24-hour blood pressure spikes due to high caffeine content. Conversely, 100% pure fruit juice exerts a protective effect (RR: 0.74) via endothelial-improving polyphenols, while honey demonstrates a neutral effect. Implications: Public health policies must implement aggressive regulatory interventions, such as taxation on SSBs and energy drinks, alongside targeted dietary counseling that differentiates between harmful liquid sugars and protective natural fruit juices.

References

Adam, L. (2019). DETERMINAN HIPERTENSI PADA LANJUT USIA. Jambura Health and Sport Journal, 1(2), 82–89. https://doi.org/10.37311/jhsj.v1i2.2558

Beigrezaei, S., Raeisi-Dehkordi, H., Hernández Vargas, J. A., Amiri, M., Artola Arita, V., van der Schouw, Y. T., Salehi-Abargouei, A., Muka, T., Chatelan, A., & Franco, O. H. (2025). Non–Sugar-Sweetened Beverages and Risk of Chronic Diseases: An Umbrella Review of Meta-analyses of Prospective Cohort Studies. Nutrition Reviews, 83(4), 663–674. https://doi.org/10.1093/nutrit/nuae135

Gentzel, M. (2025). Obesity, Metabolic Syndrome, and Sugar-Sweetened Beverages (SSBs) in America: A Novel Bioethical Argument for a Radical Public Health Proposal. Journal of Bioethical Inquiry, 22(1), 111–129. https://doi.org/10.1007/s11673-024-10369-5

He, Y., Wu, Q., Liu, D., Meng, X., & Qian, Y. (2025). Effect of dietary habits on multiple cardiovascular diseases: A comprehensive Mendelian randomization study. Medicine (United States), 104(36), e44352. https://doi.org/10.1097/MD.0000000000044352

Jamali, M., Anvarifard, P., Hosseini, B., Razaghi, M., Khorraminezhad, L., Alvandi, E., Albadawy, M., Zarezadeh, M., & Saedisomeolia, A. (2025). Sweetened beverages and cardiovascular outcomes: an umbrella review of mortality and health outcomes. Nutrition Journal, 24(1). https://doi.org/10.1186/s12937-025-01242-1

Kario, K., Okura, A., Hoshide, S., & Mogi, M. (2024). The WHO Global report 2023 on hypertension warning the emerging hypertension burden in globe and its treatment strategy. Hypertension Research, 47(5), 1099–1102. https://doi.org/10.1038/s41440-024-01622-w

Kozio?-Kozakowska, A., Wójcik, M., Herceg-?avrak, V., Cobal, S., Radovanovic, D., Alvarez-Pitti, J., Hartgring, I., Piórecka, B., Gabbianelli, R., & Dro?d?, D. (2024). Dietary Strategies in the Prevention and Treatment of Hypertension in Children and Adolescents: A Narrative Review. Nutrients, 16(16). https://doi.org/10.3390/nu16162786

Lane, M. M., Travica, N., Gamage, E., Marshall, S., Trakman, G. L., Young, C., Teasdale, S. B., Dissanayaka, T., Dawson, S. L., Orr, R., Jacka, F. N., O’Neil, A., Lawrence, M., Baker, P., Rebholz, C. M., Du, S., & Marx, W. (2024). Sugar-Sweetened Beverages and Adverse Human Health Outcomes: An Umbrella Review of Meta-Analyses of Observational Studies. Annual Review of Nutrition, 44(1), 383–404. https://doi.org/10.1146/annurev-nutr-062322-020650

Li, B., Yan, N., Jiang, H., Cui, M., Wu, M., Wang, L., Mi, B., Li, Z., Shi, J., Fan, Y., Azalati, M. M., Li, C., Chen, F., Ma, M., Wang, D., & Ma, L. (2023a). Consumption of sugar sweetened beverages, artificially sweetened beverages and fruit juices and risk of type 2 diabetes, hypertension, cardiovascular disease, and mortality: A meta-analysis. Frontiers in Nutrition, 10. https://doi.org/10.3389/fnut.2023.1019534

Li, B., Yan, N., Jiang, H., Cui, M., Wu, M., Wang, L., Mi, B., Li, Z., Shi, J., Fan, Y., Azalati, M. M., Li, C., Chen, F., Ma, M., Wang, D., & Ma, L. (2023b). Consumption of sugar sweetened beverages, artificially sweetened beverages and fruit juices and risk of type 2 diabetes, hypertension, cardiovascular disease, and mortality: A meta-analysis. Frontiers in Nutrition, 10. https://doi.org/10.3389/fnut.2023.1019534

O’Connell, S., Whelton, P. K., He, H., Li, F. X., Allouch, F., Shapiro, L., Vandenburg, M., Patel, M., Patel, A., He, J., & Mills, K. T. (2025). Abstract MP12: Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-Based Studies. Circulation, 151. https://doi.org/10.1161/cir.151.suppl_1.mp12

Pacheco, L. S., Tobias, D. K., Li, Y., Bhupathiraju, S. N., Willett, W. C., Ludwig, D. S., Ebbeling, C. B., Haslam, D. E., Drouin?Chartier, J., Hu, F. B., & Guasch?Ferré, M. (2024). Sugar-sweetened or artificially-sweetened beverage consumption, physical activity, and risk of cardiovascular disease in adults: a prospective cohort study. American Journal of Clinical Nutrition, 119(3), 669–681. https://doi.org/10.1016/j.ajcnut.2024.01.001

Qin, L., Yu, Y., & Yu, R. (2025). Artificially sweetened beverages do not influence metabolic risk factors: a systematic review and meta-analysis. Frontiers in Nutrition, 12. https://doi.org/10.3389/fnut.2025.1482719

Ralapanawa, U. (2023). RAG-SACA-2: EPIDEMIOLOGY OF HYPERTENSION IN SOUTH ASIA. Journal of Hypertension, 41. https://doi.org/10.1097/01.hjh.0000914376.72916.7e

Satoh, M., Nakayama, S., Nobayashi, H., Iwabe, Y., Izumi, S., Murakami, T., Hirose, T., & Metoki, H. (2026). Current hypertension epidemiology and contemporary approaches using the “Real-World Evidence Cycle” framework. Hypertension Research, 49(3), 756–767. https://doi.org/10.1038/s41440-025-02532-1

Schlesinger, S., Conrad, J., Amini, A. M., Buyken, A., Egert, S., Haardt, J., Kalotai, N., Kroke, A., & Schwingshackl, L. (2025). Dietary carbohydrate intake and health-related outcomes: a protocol for the evidence evaluation methodology for the new guideline on dietary carbohydrate intake of the German nutrition society. European Journal of Nutrition, 64(5). https://doi.org/10.1007/s00394-025-03744-4

Sonestedt, E., & Lukic, M. (2024a). Beverages – a scoping review for Nordic Nutrition Recommendations 2023. Food & Nutrition Research, 68. https://doi.org/10.29219/fnr.v68.10458

Sonestedt, E., & Lukic, M. (2024b). Beverages - a scoping review for nordic nutrition recommendations 2023. Food and Nutrition Research, 68. https://doi.org/10.29219/fnr.v68.10458

Sun, Y., Yu, B., Yu, Y., Wang, B., Tan, X., Lu, Y., Wang, Y., Zhang, K., & Wang, N. (2024). Sweetened Beverages, Genetic Susceptibility, and Incident Atrial Fibrillation: A Prospective Cohort Study. Circulation: Arrhythmia and Electrophysiology, 17(3), E012145. https://doi.org/10.1161/CIRCEP.123.012145

Taiso, S. N., Sudayasa, I. P., & Paddo, J. (2021). Analisis Hubungan Sosiodemografis Dengan Kejadian Hipertensi di Wilayah Kerja Puskesmas Lasalepa, Kabupaten Muna. Nursing Care and Health Technology Journal (NCHAT), 1(2), 102–109. https://doi.org/10.56742/nchat.v1i2.10

Vepsäläinen, H., & Lindström, J. (2024). Dietary patterns – a scoping review for Nordic Nutrition Recommendations 2023. Food and Nutrition Research, 68. https://doi.org/10.29219/fnr.v68.10541

Xie, H., Liu, Y., Gu, X., Liu, S., Fang, Y., Zhong, W., Zhang, Y., & Yao, S. (2024). Association between sugar-sweetened beverages and pure fruit juice with risk of six cardiovascular diseases: a Mendelian randomization study. European Journal of Clinical Nutrition, 78(8), 670–676. https://doi.org/10.1038/s41430-024-01441-9

Yunus, M. B., Aditya, I. W. C., & Eksa, D. R. (2021). HUBUNGAN USIA DAN JENIS KELAMIN DENGAN KEJADIAN HIPERTENSI DI PUSKESMAS HAJI PEMANGGILAN KECAMATAN ANAK TUHA KAB. LAMPUNG TENGAH. JURNAL ILMU KEDOKTERAN DAN KESEHATAN, 8(3). https://doi.org/10.33024/jikk.v8i3.5193

Zhang, Z., Li, W., Zhang, M., & Zhang, Y. (2026). High sugar-sweetened beverage intake predicts adverse physical, emotional, and sleep health trajectories in adolescents: a 4-year prospective cohort study. Frontiers in Public Health, 13. https://doi.org/10.3389/fpubh.2025.1754072

Zhao, Y., Feng, Y., Zeng, Y., Di, W., Luo, X., Wu, X., Guan, R., Xu, L., Yang, X., Li, Y., Wu, Y., Wu, X., Zhang, Y., Li, X., Qin, P., Hu, F., Hu, D., Li, H., & Zhang, M. (2023). Sugar intake and risk of hypertension: a systematic review and dose–response meta-analysis of cohort and cross-sectional studies. Critical Reviews in Food Science and Nutrition, 64(26), 1–12. https://doi.org/10.1080/10408398.2023.2213330

Zhou, B., Perel, P., Mensah, G. A., & Ezzati, M. (2021). Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension. Nature Reviews Cardiology, 18(11), 785–802. https://doi.org/10.1038/s41569-021-00559-8

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Published

2026-06-30

How to Cite

Istyanto, F. ., Liza Virgianti, Ika Wijayanti, & Sophian Aswar. (2026). Minuman Manis dan Hipertensi dalam Perspektif Epidemiologi: Sintesis Bukti Ilmiah . JURNAL KESEHATAN TROPIS INDONESIA, 4(3), 1022–1029. https://doi.org/10.63265/jkti.v4i3.285