Faktor yang Memengaruhi Siklus Menstruasi Pada Mahasiswi : An Occupational Health Study

Authors

  • Anis Satus Syarifah Program Studi Sarjana Keselamatan dan Kesehatan Kerja, Sekolah Tinggi Ilmu Kesehatan Pemkab Jombang
  • Fitri Firranda Nurmalisyah Program Studi Sarjana Keselamatan dan Kesehatan Kerja, Sekolah Tinggi Ilmu Kesehatan Pemkab Jombang
  • Rodiyah Sekolah Tinggi Ilmu Kesehatan Pemkab Jombang
  • Eko Sih Panglipuringtyas Sekolah Tinggi Ilmu Kesehatan Pemkab Jombang
  • Laely Ufiz Tsani Sugiyana Program Studi Sarjana Keselamatan dan Kesehatan Kerja Universitas Muhammadiyah Lamongan

DOI:

https://doi.org/10.63265/jkti.v3i4.236

Keywords:

college students, menstrual cycle, occupational health, stress

Abstract

Kesehatan menstruasi merupakan indikator penting bagi kesejahteraan reproduksi perempuan. Di lingkungan perguruan tinggi, mahasiswi menghadapi berbagai tekanan akademik dan lingkungan yang dapat bertindak sebagai risiko kesehatan kerja yang memengaruhi siklus menstruasi mereka.  Systematic review ini bertujuan untuk mengidentifikasi dan menganalisis faktor gaya hidup, psikososial, dan biologis yang memengaruhi ketidakteraturan siklus menstruasi pada mahasiswi.  Menggunakan panduan PRISMA, pencarian sistematis dilakukan pada database PubMed dan Scopus untuk artikel yang terbit antara tahun 2021 dan 2026. Sebanyak 23 artikel studi cross-sectional dan case-control memenuhi kriteria inklusi dan disintesis dalam penelitian ini.  Temuan studi secara konsisten mengidentifikasi stres psikologis (stres akademik dan depresi) sebagai prediktor paling dominan terhadap gangguan menstruasi melalui gangguan pada aksis hipotalamus-hipofisis-adrenal (HPA). Selain itu, kualitas tidur yang buruk/insomnia, Indeks Massa Tubuh (IMT) ekstrem (terlalu kurus dan kelebihan berat badan/obesitas), gaya hidup sedenter, serta pola makan yang buruk (asupan lemak tinggi, kebiasaan melewatkan makan) secara signifikan meningkatkan risiko dismenore, siklus tidak teratur, dan Premenstrual Syndrome (PMS). Sebaliknya, konsumsi makanan kaya vitamin A memberikan efek perlindungan. Gangguan menstruasi di kalangan mahasiswi memiliki prevalensi tinggi dan bersifat multifaktorial. Promosi kesehatan di kampus perlu menerapkan program manajemen stres serta edukasi kebersihan tidur dan nutrisi guna mendukung kesehatan reproduksi mahasiswi.

References

Abbas, K., Usman, G., Ahmed, M., Qazi, R., Asghar, A., Masood Shah, A., Rizvi, A., Abid, K., Haq, K. U., Tahir, A., & Usama, S. M. (2020). Physical and Psychological Symptoms Associated With Premenstrual Syndrome and Their Impact on the Daily Routine of Women in a Low Socioeconomic Status Locality. Cureus. https://doi.org/10.7759/cureus.10821

Afzal, B., Hussain, S., Gul, S., & Hamid, S. (2024). Prevalence of Dysmenorrhea and Predictors of Its Pain Intensity Among Female Medical Students: A Cross Sectional Study. Journal of Islamic International Medical College (JIIMC), 19(3), 157–164.

Alhammadi, M. H., Albogmi, A. M., Alzahrani, M. K., Shalabi, B. H., Fatta, F. A., & AlBasri, S. F. (2022). Menstrual cycle irregularity during examination among female medical students at King Abdulaziz University, Jeddah, Saudi Arabia. BMC Women’s Health, 22(1), 367. https://doi.org/10.1186/s12905-022-01952-2

Alkhatib, A., Zhou, Q., Bajinka, O., Pakwan Suwal, R., Wiley, J., & Li, X. (2022). Prevalence of menstrual symptoms change and influencing factors among international female students studying in china during acculturation period. BMC Women’s Health, 22(1), 311. https://doi.org/10.1186/s12905-022-01897-6

Aolymat, I., Al-Tamimi, M., Almomani, H., Abu-Hassan, D. W., Alzayadneh, E. M., Al-Husban, N., Al Haj Mahmoud, S., & Alsheikh, A. (2023). COVID-19-associated mental health impact on menstruation physiology: A survey study among medical students in Jordan. Women’s Health, 19, 17455057221150099. https://doi.org/10.1177/17455057221150099

Baker, F. C., & Lee, K. A. (2022). Menstrual Cycle Effects on Sleep. Commemorative Issue: 15 Years of the Sleep Medicine Clinics – PART 1: Sleep and Sleep Disorders, 17(2), 283–294. https://doi.org/10.1016/j.jsmc.2022.02.004

BARNARD, N. D., SCIALLI, A. R., HURLOCK, D., & BERTRON, P. (2000). Diet and Sex-Hormone Binding Globulin, Dysmenorrhea, and Premenstrual Symptoms. Obstetrics & Gynecology, 95(2). https://journals.lww.com/greenjournal/fulltext/2000/02000/diet_and_sex_hormone_binding_globulin,.15.aspx

Dimlievych, A., D?bska, G., Grzesik-G?sior, J., & Merklinger-Gruchala, A. (2025). Perceived Menstrual Irregularities and Premenstrual Syndrome in Relation to Insomnia: Evidence from a Cohort of Student Nurses. Journal of Clinical Medicine, 14(21), 7470. https://doi.org/10.3390/jcm14217470

Eva, S. K., Aufi, S. S., Mamun, A. S. M. A., Sabiruzzaman, M., Wadood, M. A., & Hossain, M. G. (2024). Depression and its association with menstrual disturbance among female university students: A cross-sectional study. BMJ Public Health, 2(2), e000716. https://doi.org/10.1136/bmjph-2023-000716

Fitri, S., Sofianita, N. I., & Octaria, Y. C. (2024). Faktor yang Mempengaruhi Siklus Menstruasi pada Mahasiswi di Depok, Indonesia: Factors Influencing the Menstrual Cycle of Female College Students in Depok, Indonesia. Amerta Nutrition, 8(3SP), 94–104. https://doi.org/10.20473/amnt.v8i3SP.2024.94-104

Franco-Antonio, C., Santano-Mogena, E., & Cordovilla-Guardia, S. (2025). Dysmenorrhea, Premenstrual Syndrome, and Lifestyle Habits in Young University Students in Spain: A Cross-Sectional Study. Journal of Nursing Research, 33(1), e374. https://doi.org/10.1097/jnr.0000000000000657

Kementerian Kesehatan RI. (2018). Hasil Riskesdas 2018. Kementerian Kesehatan Republik Indonesia.

M, B. T., Daniyal J, Venmathy S, Kowsalya B, & Samal, J. (2025). Prevalence and Associated Factors of Dysmenorrhea Among University Students in Tamil Nadu, India: A Cross-Sectional Study. National Journal of Community Medicine, 16(01), 1–7. https://doi.org/10.55489/njcm.160120254550

Matsuura, Y., Abe, Y., Motoki, Y., Tran, N. H., & Yasui, T. (2023). Menstrual Abnormalities in Female International Students in Japan: Changes during Pre-Arrival, Difficult, and Current Periods. European Journal of Investigation in Health, Psychology and Education, 13(7), 1362–1377. https://doi.org/10.3390/ejihpe13070099

Mittiku, Y. M., Mekonen, H., Wogie, G., Tizazu, M. A., & Wake, G. E. (2022). Menstrual irregularity and its associated factors among college students in Ethiopia, 2021. Frontiers in Global Women’s Health, 3, 917643. https://doi.org/10.3389/fgwh.2022.917643

Naz, M. S. G., Farahmand, M., Dashti, S., & Tehrani, F. R. (2022). Factors Affecting Menstrual Cycle Developmental Trajectory in Adolescents: A Narrative Review. International Journal of Endocrinology and Metabolism, 20(1). https://doi.org/10.5812/ijem.120438

Nguyen, N. T., & Le, T. T. M. (2024). Factors predicting menstrual irregularity among university students in Ho Chi Minh City, Vietnam: A cross-sectional study. Belitung Nursing Journal, 10(4), 424–429. https://doi.org/10.33546/bnj.3303

Nori, W., Hameed, B. H., Murshid, R. M., & Akram, W. (2025). The impact of stress on menstrual cycle changes around examination time among medical college students: A multicentric study. Italian Journal of Gynæcology & Obstetrics, 37(4), 369–380. https://doi.org/10.36129/jog.2024.215

Novelia, S., Syamsiah, S., & Wenola, W. (2023). The Relationship of Stress Levels and Menstrual Cycle among Female Students. Health and Technology Journal (HTechJ), 1(4), 381–385. https://doi.org/10.53713/htechj.v1i4.44

Núñez-Troconis, J. T., Carvallo-Ruiz, D. E., Martínez-Núñez, E. N., & Núñez-Urdaneta, R. A. (2024). Psychosocial stress as a predisposing risk factor of primary dysmenorrhea: A Venezuelan cross-sectional study. Revista Chilena de Obstetricia y Ginecología, 89(4), 14348. https://doi.org/10.24875/RECHOG.23000137

Sadiqi, M. A. E., & Salih, A. A. (2024). The effect of psychological stress on the menstrual cycle among medical students. Journal of the Pakistan Medical Association, 74(10 (Supple-08)), S164–S167. https://doi.org/10.47391/JPMA-BAGH-16-36

Sen, L. C., Jahan, I., Salekin, N., Shourove, J. H., Rahman, M., Uddin, M. J., Zhang, C., H. Hamer, D., & Islam, G. M. R. (2024). Food craving, vitamin A, and menstrual disorders: A comprehensive study on university female students. PLOS ONE, 19(9), e0310995. https://doi.org/10.1371/journal.pone.0310995

Singh, P., Sharma, C., Krishna, S., Mishra, V., Yadav, G., Patwa, P., Gothwal, M., & Jhirwal, M. (2022). Lifestyle and Prevalence of Menstrual Disorders among Undergraduate Medical and Nursing Students: Can We Bring a Change? The Journal of Obstetrics and Gynecology of India, 72(S1), 326–333. https://doi.org/10.1007/s13224-021-01606-7

Sualeh, M., Uddin, M. R., Junaid, N., Khan, M., Pario, A., & Ain, Q. (2022). Impact of COVID-19 Vaccination on Menstrual Cycle: A Cross-Sectional Study From Karachi, Pakistan. Cureus. https://doi.org/10.7759/cureus.28630

Tadese, M., Kassa, A., Muluneh, A. A., & Altaye, G. (2021). Prevalence of dysmenorrhoea, associated risk factors and its relationship with academic performance among graduating female university students in Ethiopia: A cross-sectional study. BMJ Open, 11(3), e043814. https://doi.org/10.1136/bmjopen-2020-043814

Tadesse, A. W., Abebe, N. M., Tadesse3, S. E., Wube, M. C., & Abate, A. A. (2021). Preventive Practice and Associated Factors towards COVID-19 among College Students in Amhara Region, Ethiopia: A Cross- Sectional Study. Ethiopian Journal of Health Sciences, 31(1). https://doi.org/10.4314/ejhs.v31i1.2

Than, W. W., Hossain Parash, M. T., Binti Abdul Majeed, N., Nyein Yin, K., Pg Baharuddin, D. M. B., Fahmy, E. H. A. M., & Mohd Daud, M. N. B. (2023). A Case-Control Study on Factors Associated With Secondary Amenorrhea Among the Medical Students of Universiti Malaysia Sabah. Cureus. https://doi.org/10.7759/cureus.47625

The American College of Obstetricians and Gynecologists. (2015). Menstruation in Girls and Adolescents: Using the Menstrual Cycle as a Vital Sign. (651).

Tomar, A., Deepshikha, Das, S. C., Juyal, R., Kaur, G., & Jain, R. (2025). Exploring the Relationship Between Perceived Stress and Menstrual Health in Undergraduates Across Different Academic Disciplines. Indian Journal of Community Health, 37(2), 295–301. https://doi.org/10.47203/IJCH.2025.v37i02.019

Upadhyay, M., Mahishale, A., & Kari, A. (2023). Prevalence of premenstrual syndrome in college going girls—A cross sectional study. Clinical Epidemiology and Global Health, 20, 101234. https://doi.org/10.1016/j.cegh.2023.101234

WHO. (2022). WHO statement on menstrual health and rights. https://www.who.int/news/item/22-06-2022-who-statement-on-menstrual-health-and-rights

Zeru, A. B., Gebeyaw, E. D., & Ayele, E. T. (2021). Magnitude and associated factors of menstrual irregularity among undergraduate students of Debre Berhan University, Ethiopia. Reproductive Health, 18(1), 101. https://doi.org/10.1186/s12978-021-01156-1

Zhuang, Y., Kwang Cheol, K., Botabara-Yap, M. J., Zhao, K., Ramos, R. I. A., & Cao, W. (2025). Factors associated with reproductive health and health education participation among female college students in China. Frontiers in Public Health, 13, 1627669. https://doi.org/10.3389/fpubh.2025.1627669

Downloads

Published

2025-09-20

How to Cite

Syarifah, A. S., Nurmalisyah, F. F., Rodiyah, Panglipuringtyas, E. S., & Sugiyana, L. U. T. . (2025). Faktor yang Memengaruhi Siklus Menstruasi Pada Mahasiswi : An Occupational Health Study. JURNAL KESEHATAN TROPIS INDONESIA, 3(4), 286–310. https://doi.org/10.63265/jkti.v3i4.236